The rate-limiting step for glucose transport into the hypothalamus is across the blood-hypothalamus interface
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چکیده
منابع مشابه
The rate-limiting step for glucose transport into the hypothalamus is across the blood-hypothalamus interface.
Specialized glucosensing neurons are present in the hypothalamus, some of which neighbor the median eminence, where the blood-brain barrier has been reported leaky. A leaky blood-brain barrier implies high tissue glucose levels and obviates a role for endothelial glucose transporters in the control of hypothalamic glucose concentration, important in understanding the mechanisms of glucose sensi...
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ژورنال
عنوان ژورنال: Journal of Neurochemistry
سال: 2009
ISSN: 0022-3042,1471-4159
DOI: 10.1111/j.1471-4159.2009.05934.x